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INSULIN, ISOPHANE
Descriptors Found:
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DeCS
Descriptor
English
:
Insulin, Isophane
Descriptor
Spanish
:
Insulina Isófana
Descriptor
Portuguese
:
Insulina Isófana
Synonyms
English
:
Insulin, NPH
Tree Number:
D06.472.699.587.200.300.200
D12.644.548.586.200.300.200
Definition
English
:
An intermediate-acting
INSULIN
preparation with onset time of 2 hours and duration of 24 hours. It is produced by crystallizing ZINC-insulin-PROTAMINES at neutral pH 7. Thus it is called neutral protamine Hagedorn for inventor Hans Christian Hagedorn.
Pharmacological Action:
Hypoglycemic Agents
Entry Combination - descr/qualif
English
:
Insulin, Isophane
/
antagonists & inhibitors
use
Insulin Antagonists
History Note
English
:
2009 (1963); for INSULIN, PROTAMINE ZINC use INSULIN, LONG-ACTING 1966-2011
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UR
urine
Record Number:
7505
Unique Identifier:
D007336
Occurrence in VHL
:
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